According to a 2018 review, statins may cause temporary memory impairment, but they may also have a protective effect against age-related cognitive decline. In addition, statins may slightly increase a person’s risk of type 2 diabetes.įinally, statins may be linked with memory problems, though the evidence has been mixed. However, a 2017 review found no clear evidence of this. More rarely still, a severe type of muscle damage called rhabdomyolysis may occur, in an estimated 2–3 in 100,000 people taking this type of drug per year.Īlso, some research has linked statin use with cataracts. The damage is typically reversible once the person stops taking the statin. Specifically, statins may lead to muscle damage in 1 in 10,000 people who take this type of drug each year. The two most serious side effects are liver failure and skeletal muscle damage. ![]() Most people who take statins have minor side effects, if any. People who are taking simvastatin, atorvastatin, or lovastatin should avoid grapefruit and grapefruit juice to reduce the risk of an interaction. For instance, Vytorin is a combination of simvastatin, which is a statin, and ezetimibe, a drug that reduces the absorption of dietary cholesterol. In addition, statins can lower the amount of fats, called triglycerides, in the blood.Ītorvastatin and rosuvastatin are the most potent, while fluvastatin is the least.Ĭombination drugs are also available. Statins can also raise levels of high-density lipoprotein (HDL), or “good,” cholesterol. People sometimes refer to this type as “bad” cholesterol. Statins can reduce the amount of low-density lipoprotein (LDL) cholesterol in the body. ![]() They are also known as HMG-CoA reductase inhibitors. These drugs block the action of a liver enzyme that helps produce cholesterol. ![]() Doctors typically prescribe statins to lower blood cholesterol levels.
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